dandiarchive-dataset/s3://dandiarchive/dandisets/001047/draft/dandiset.yaml

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assetsSummary:
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citation: Silkuniene, Giedre; Silkunas, Mantas; Pakhomov, Andrei (2025) Optimizing
  NG-CanCan Protocol Delivery with MHz Compression to Minimize Near-Electrode Ablation
  (Version draft) [Data set]. DANDI Archive. https://dandiarchive.org/dandiset/001047/draft
contributor:
- affiliation: []
  email: giedre.silkuniene@gmail.com
  identifier: 0000-0001-8436-9718
  includeInCitation: true
  name: Silkuniene, Giedre
  roleName:
  - dcite:ContactPerson
  schemaKey: Person
- identifier: 0000-0002-4568-9265
  includeInCitation: true
  name: Silkunas, Mantas
  schemaKey: Person
- identifier: 0000-0003-3816-3860
  includeInCitation: true
  name: Pakhomov, Andrei
  roleName:
  - dcite:ProjectLeader
  schemaKey: Person
- awardNumber: 1R21EY034258
  includeInCitation: false
  name: National Institutes of Health
  roleName:
  - dcite:Funder
  schemaKey: Organization
- identifier: 0000-0002-0302-1355
  name: Semenov, Iurii
  schemaKey: Person
- identifier: 0000-0003-4950-4130
  name: Pakhomova, Olga
  schemaKey: Person
dateCreated: '2024-06-04T17:21:04.141576+00:00'
description: This study advanced the Next Generation (NG) CanCan protocols by implementing
  MHz compression for electric pulse packet delivery. Packets were delivered at 0.2
  MHz, and the compression significantly reduced near-electrode cell ablation compared
  to delivery at 1 Hz, while preserving effects at the center. The experiments used
  a four-electrode array, with YoPro-1 to evaluate cell permeabilization and Propidium
  Iodide to assess cell death two hours post-delivery. This work was supported by
  NIH grant 1R21EY034258.
ethicsApproval: []
id: DANDI:001047/draft
identifier: DANDI:001047
license:
- spdx:CC-BY-4.0
manifestLocation:
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name: Optimizing NG-CanCan Protocol Delivery with MHz Compression to Minimize Near-Electrode
  Ablation
relatedResource:
- identifier: doi.org/10.1016/j.bioelechem.2025.109016
  name: MHz compression of pulse packets facilitates remote focusing of electroporation
  relation: dcite:IsPublishedIn
  resourceType: dcite:JournalArticle
  schemaKey: Resource
  url: https://doi.org/10.1016/j.bioelechem.2025.109016
repository: https://dandiarchive.org
schemaKey: Dandiset
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url: https://dandiarchive.org/dandiset/001047/draft
version: draft
wasGeneratedBy:
- identifier: NIH 1R21EY034258
  name: Targeted Neuromodulation by Nanosecond Pulsed Electric Fields
  schemaKey: Project