DagsHub-Datasets
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dandiarchive-dataset


  
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            {"id":"DANDI:001047/0.241211.1856","url":"https://dandiarchive.org/dandiset/001047/0.241211.1856","name":"Optimizing NG-CanCan Protocol Delivery with MHz Compression to Minimize Near-Electrode Ablation","about":[],"access":[{"status":"dandi:OpenAccess","schemaKey":"AccessRequirements"}],"license":["spdx:CC-BY-4.0"],"version":"0.241211.1856","@context":"https://raw.githubusercontent.com/dandi/schema/master/releases/0.6.7/context.json","citation":"Silkuniene, Giedre; Silkunas, Mantas; Pakhomov, Andrei (2024) Optimizing NG-CanCan Protocol Delivery with MHz Compression to Minimize Near-Electrode Ablation (Version 0.241211.1856) [Data set]. DANDI archive. https://dandiarchive.org/dandiset/001047/0.241211.1856","keywords":[],"protocol":[],"schemaKey":"Dandiset","identifier":"DANDI:001047","repository":"https://dandiarchive.org","contributor":[{"name":"Silkuniene, Giedre","email":"giedre.silkuniene@gmail.com","roleName":["dcite:ContactPerson"],"schemaKey":"Person","identifier":"0000-0001-8436-9718","affiliation":[],"includeInCitation":true},{"name":"Silkunas, Mantas","schemaKey":"Person","identifier":"0000-0002-4568-9265","includeInCitation":true},{"name":"Pakhomov, Andrei","roleName":["dcite:ProjectLeader"],"schemaKey":"Person","identifier":"0000-0003-3816-3860","includeInCitation":true},{"name":"National Institutes of Health","roleName":["dcite:Funder"],"schemaKey":"Organization","awardNumber":"1R21EY034258","includeInCitation":false}],"dateCreated":"2024-06-04T17:21:04.141576+00:00","description":"This study advanced the Next Generation (NG) CanCan protocols by implementing MHz compression for electric pulse packet delivery. Packets were delivered at 0.2 MHz, and the compression significantly reduced near-electrode cell ablation compared to delivery at 1 Hz, while preserving effects at the center. The experiments used a four-electrode array, with YoPro-1 to evaluate cell permeabilization and Propidium Iodide to assess cell death two hours post-delivery. This work was supported by NIH grant 1R21EY034258.","publishedBy":{"id":"urn:uuid:66b9cd54-2497-4916-bddc-89ab80e4529d","name":"DANDI publish","endDate":"2024-12-11T18:56:01.408053+00:00","schemaKey":"PublishActivity","startDate":"2024-12-11T18:56:01.408053+00:00","wasAssociatedWith":[{"id":"urn:uuid:8acf2290-06fe-4c56-953c-3d00e0d273d3","name":"DANDI API","version":"0.1.0","schemaKey":"Software","identifier":"RRID:SCR_017571"}]},"studyTarget":[],"assetsSummary":{"species":[{"name":"Mus musculus - House mouse","schemaKey":"SpeciesType","identifier":"http://purl.obolibrary.org/obo/NCBITaxon_10090"},{"name":"Cricetulus griseus - Cricetulus aureus","schemaKey":"SpeciesType","identifier":"http://purl.obolibrary.org/obo/NCBITaxon_10029"}],"approach":[],"schemaKey":"AssetsSummary","dataStandard":[{"name":"Neurodata Without Borders (NWB)","schemaKey":"StandardsType","identifier":"RRID:SCR_015242"}],"numberOfBytes":17250416220,"numberOfFiles":88,"numberOfSubjects":29,"variableMeasured":[],"measurementTechnique":[]},"datePublished":"2024-12-11T18:56:01.408053+00:00","schemaVersion":"0.6.7","ethicsApproval":[],"wasGeneratedBy":[{"name":"Targeted Neuromodulation by Nanosecond Pulsed Electric Fields","schemaKey":"Project","identifier":"NIH 1R21EY034258"}],"relatedResource":[],"manifestLocation":["https://dandiarchive.s3.amazonaws.com/dandisets/001047/0.241211.1856/assets.yaml"]}