dandiarchive-dataset/s3://dandiarchive/dandisets/000947/0.240510.2211/dandiset.yaml

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about:
- identifier: http://purl.obolibrary.org/obo/UBERON_0002477
  name: medial globus pallidus
  schemaKey: Anatomy
- identifier: http://purl.obolibrary.org/obo/UBERON_0001384
  name: primary motor cortex
  schemaKey: Anatomy
- identifier: http://purl.obolibrary.org/obo/UBERON_0001925
  name: ventral lateral nucleus of thalamus
  schemaKey: Anatomy
access:
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  status: dandi:OpenAccess
assetsSummary:
  approach:
  - name: electrophysiological approach
    schemaKey: ApproachType
  dataStandard:
  - identifier: RRID:SCR_015242
    name: Neurodata Without Borders (NWB)
    schemaKey: StandardsType
  measurementTechnique:
  - name: analytical technique
    schemaKey: MeasurementTechniqueType
  - name: surgical technique
    schemaKey: MeasurementTechniqueType
  - name: multi electrode extracellular electrophysiology recording technique
    schemaKey: MeasurementTechniqueType
  - name: spike sorting technique
    schemaKey: MeasurementTechniqueType
  numberOfBytes: 1048819909625
  numberOfFiles: 378
  numberOfSubjects: 2
  schemaKey: AssetsSummary
  species:
  - identifier: http://purl.obolibrary.org/obo/NCBITaxon_9544
    name: Macaca mulatta - Rhesus monkey
    schemaKey: SpeciesType
  variableMeasured:
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  - ElectrodeGroup
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citation: Kase, Daisuke; Han, Yan; Zimnik, Andrew; Cox, Karin; Turner, Robert (2024)
  Reach-related Single Unit Activity in the Parkinsonian Macaque (Version 0.240510.2211)
  [Data set]. DANDI archive. https://dandiarchive.org/dandiset/000947/0.240510.2211
contributor:
- email: daisuke.kase@pitt.edu
  identifier: 0000-0002-3837-162X
  includeInCitation: true
  name: Kase, Daisuke
  roleName:
  - dcite:Author
  - dcite:DataCollector
  schemaKey: Person
- includeInCitation: true
  name: Han, Yan
  roleName:
  - dcite:DataCollector
  schemaKey: Person
- includeInCitation: true
  name: Zimnik, Andrew
  roleName:
  - dcite:Author
  - dcite:DataCollector
  schemaKey: Person
- email: kmc51@pitt.edu
  identifier: 0000-0002-5418-0508
  includeInCitation: true
  name: Cox, Karin
  roleName:
  - dcite:Author
  - dcite:DataCollector
  schemaKey: Person
- email: rturner@pitt.edu
  identifier: 0000-0002-6074-4365
  includeInCitation: true
  name: Turner, Robert
  roleName:
  - dcite:Author
  - dcite:ContactPerson
  schemaKey: Person
- awardNumber: ASAP-020519
  identifier: https://ror.org/03zj4c476
  includeInCitation: false
  name: Aligning Science Across Parkinson's (ASAP)
  roleName:
  - dcite:Funder
  schemaKey: Organization
- awardNumber: 1 R01 NS 117058-01
  identifier: https://ror.org/01cwqze88
  includeInCitation: false
  name: National Institutes of Health (NIH)
  roleName:
  - dcite:Funder
  schemaKey: Organization
- awardNumber: 1 R01 NS 070865-01A1
  identifier: https://ror.org/01cwqze88
  includeInCitation: false
  name: National Institutes of Health (NIH)
  roleName:
  - dcite:Funder
  schemaKey: Organization
dateCreated: '2024-03-30T12:27:06.991378+00:00'
datePublished: '2024-05-10T22:11:16.460019+00:00'
description: 'This dataset contains recordings of single-unit activity from from multiple
  brain areas,  including globus pallidus-internus (GPi), ventrolateral nucleus of
  the thalamus (VLa and VLp) and the arm-related regions of primary motor cortex,
  including sulcus (M1-S) and gyrus (M1-G) subregions, in monkeys performing a choice
  reaction time reaching task. Small numbers of recordings were also obtained from
  supplementary motor area (SMA), external globus pallidus (GPe), the thalamic reticular
  nucleus (RTN), striatum (STR) and the region between RTN and VL thalamus (R-V).
  It contains data from two monkeys before and after the administration of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine),
  which induces Parkinsonism. The neuronal activity was recorded using 16-contact
  linear probes (0.5–1.0 MΩ, V-probe, Plexon) or glass-insulated tungsten microelectrodes
  (0.5–1.5 MΩ, Alpha Omega). The neuronal data were amplified (4×, 2 Hz–7.5 kHz) and
  digitized at 24.414 kHz (approx., 16-bit resolution; Tucker Davis Technologies).
  The neuronal data were high-pass filtered (Fpass: 200 Hz, Matlab FIRPM) and thresholded,
  and candidate action potentials were sorted into clusters in principal components
  space (Off-line Sorter, Plexon or custom algorithm, TomSort, https://zenodo.org/doi/10.5281/zenodo.11176978).


  The recordings for subject Isis before the administration of MPTP (pre-MPTP) were
  collected by Daisuke Kase.

  The recordings for subject Isis after the administration of MPTP (post-MPTP) were
  collected by Yan Han (韩妍).

  The recordings for subject Gaia (pre-MPTP,  post-MPTP) from 2015 were collected
  by Andrew J. Zimnik.

  The recordings for subject Gaia (post-MPTP) from 2016-2017 were also collected by
  Daisuke Kase.'
ethicsApproval: []
id: DANDI:000947/0.240510.2211
identifier: DANDI:000947
keywords:
- extracellular electrophysiology
- single-unit activity
- globus pallidus-internus
- macaque
- reaching
- Parkinson's disease
- ventrolateral thalamus
- primary motor cortex
license:
- spdx:CC-BY-4.0
manifestLocation:
- https://dandiarchive.s3.amazonaws.com/dandisets/000947/0.240510.2211/assets.yaml
name: Reach-related Single Unit Activity in the Parkinsonian Macaque
protocol: []
publishedBy:
  endDate: '2024-05-10T22:11:16.460019+00:00'
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    name: DANDI API
    schemaKey: Software
    version: 0.1.0
relatedResource:
- identifier: https://doi.org/10.1371/journal.pbio.3000829
  name: Neural activity during a simple reaching task in macaques is counter to gating
    and rebound in basal ganglia-thalamic communication
  relation: dcite:IsDescribedBy
  repository: PLOS Biology
  resourceType: dcite:JournalArticle
  schemaKey: Resource
  url: https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000829
- identifier: ''
  name: Reach-related Single Unit Activity in the Parkinsonian Macaque
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  repository: example-notebooks
  resourceType: dcite:ComputationalNotebook
  schemaKey: Resource
  url: https://github.com/dandi/example-notebooks/blob/master/000947/TurnerLab/public_demo/000947_demo.ipynb
- identifier: https://doi.org/10.1101/2023.09.08.556120
  name: Detecting rhythmic spiking through the power spectra of point process model
    residuals
  relation: dcite:IsDescribedBy
  repository: bioRxiv
  resourceType: dcite:Preprint
  schemaKey: Resource
  url: https://www.biorxiv.org/content/10.1101/2023.09.08.556120v2
repository: https://dandiarchive.org
schemaKey: Dandiset
schemaVersion: 0.6.7
studyTarget: []
url: https://dandiarchive.org/dandiset/000947/0.240510.2211
version: 0.240510.2211
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