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  1. '@context': https://raw.githubusercontent.com/dandi/schema/master/releases/0.6.7/context.json
  2. about: []
  3. access:
  4. - schemaKey: AccessRequirements
  5. status: dandi:OpenAccess
  6. assetsSummary:
  7. numberOfBytes: 0
  8. numberOfFiles: 0
  9. schemaKey: AssetsSummary
  10. citation: Ramachandran, Sandhya; Gao, Huan; Yu, Kai; He, Bin (2025) Neural Spiking
  11. Data in the Awake Rat Somatosensory Cortex Responding to Trials of Transcranial
  12. Focused Ultrasound Stimulation (Version draft) [Data set]. DANDI Archive. https://dandiarchive.org/dandiset/000945/draft
  13. contributor:
  14. - affiliation: []
  15. email: s.ramachandran8@gmail.com
  16. includeInCitation: true
  17. name: Ramachandran, Sandhya
  18. roleName:
  19. - dcite:ContactPerson
  20. - dcite:Author
  21. schemaKey: Person
  22. - includeInCitation: true
  23. name: Gao, Huan
  24. roleName:
  25. - dcite:Author
  26. schemaKey: Person
  27. - includeInCitation: true
  28. name: Yu, Kai
  29. roleName:
  30. - dcite:Author
  31. schemaKey: Person
  32. - includeInCitation: true
  33. name: He, Bin
  34. roleName:
  35. - dcite:Author
  36. schemaKey: Person
  37. - includeInCitation: false
  38. name: Carnegie Mellon University
  39. roleName:
  40. - dcite:Affiliation
  41. schemaKey: Organization
  42. - includeInCitation: false
  43. name: NIH NS124564
  44. roleName:
  45. - dcite:Funder
  46. schemaKey: Organization
  47. - includeInCitation: false
  48. name: NIH EB029354
  49. roleName:
  50. - dcite:Funder
  51. schemaKey: Organization
  52. - includeInCitation: false
  53. name: NIH NS131069
  54. roleName:
  55. - dcite:Funder
  56. schemaKey: Organization
  57. dateCreated: '2024-03-30T03:06:13.114761+00:00'
  58. description: 'In these recordings, we tested different PRFs (pulse repetition frequencies)
  59. of ultrasound stimulation using a 128-element random array ultrasound transducer
  60. to stimulate the somatosensory cortex of awake head-fixed rats. Chronic electrophysiological
  61. recordings were acquired using 32-channel NeuroNexus electrodes (Model: A1x32-Poly3-10mm-50-177-Z32),
  62. chronically implanted into the rat brain. Ultrasound stimulation is delivered every
  63. 2.5 seconds with a 10% jitter, and each recording has 500 trials. The PRFs tested
  64. were 30 Hz, 300 Hz, 1500 Hz, 3000 Hz, and 4500 Hz, each with a 200 microsecond pulse
  65. duration and a 67 ms ultrasound duration. Anesthetized files were performed under
  66. 2% isoflurane anesthesia for comparison.File InformationAll 10 subjects were male
  67. rats, implanted with their chronic electrode at 6 months of age and then recordings
  68. taken first at 8-10 months, and then some repeats taken at 12 months. Within each
  69. subject''s folder are recordings for the different PRFs. Most subjects have 5 recordings
  70. within, one for each PRF. Some subjects have duplicate recordings taken a few months
  71. after the original ones. A few recordings were not included due to excessive noise
  72. in the recordings. Files are named in the format SubjectName_PRF_PulseDuration.
  73. Each file contains spike time data with the cell type labels included for each neurons,
  74. as well as time series data for the onset of each trial of ultrasound stimulation.
  75. Detailed description about this dataset can be found in the following publication.
  76. Please cite the paper if you would use a portion of the dataset. Ramachandran, Sandhya
  77. et al. “Parameter-dependent cell-type specific effects of transcranial focused ultrasound
  78. stimulation in an awake head-fixed rodent model.” Journal of neural engineering
  79. vol. 22,2 026022. 19 Mar. 2025, doi:10.1088/1741-2552/adbb1f'
  80. ethicsApproval: []
  81. id: DANDI:000945/draft
  82. identifier: DANDI:000945
  83. license:
  84. - spdx:CC-BY-4.0
  85. manifestLocation:
  86. - https://api.dandiarchive.org/api/dandisets/000945/versions/draft/assets/
  87. name: Neural Spiking Data in the Awake Rat Somatosensory Cortex Responding to Trials
  88. of Transcranial Focused Ultrasound Stimulation
  89. relatedResource: []
  90. repository: https://dandiarchive.org
  91. schemaKey: Dandiset
  92. schemaVersion: 0.6.7
  93. url: https://dandiarchive.org/dandiset/000945/draft
  94. version: draft
  95. wasGeneratedBy: []
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