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- {"id":"DANDI:000935/0.240319.2026","url":"https://dandiarchive.org/dandiset/000935/0.240319.2026","name":"Interluminescence: Selective Control of Synaptically-Connected Circuit Elements using bioluminescence","about":[],"access":[{"status":"dandi:OpenAccess","schemaKey":"AccessRequirements"}],"license":["spdx:CC-BY-4.0"],"version":"0.240319.2026","@context":"https://raw.githubusercontent.com/dandi/schema/master/releases/0.6.6/context.json","citation":"Prakash, Mansi; Murphy, Jeremy; Friedman, Nina; Pal, Akash; Bhagat, Yuvraj; Shaner, Nathan C.; Lipscombe, Diane; Hochgeschwender, Ute; Moore, Christopher I.; Crespo, Emmanuel L. (2024) Interluminescence: Selective Control of Synaptically-Connected Circuit Elements using bioluminescence (Version 0.240319.2026) [Data set]. DANDI archive. https://dandiarchive.org/dandiset/000935/0.240319.2026","keywords":["Bioluminescence","Luminopsins","Parvalbumin","gamma rhythms"],"protocol":["https://doi.org/10.1038/s42003-021-02981-7"],"schemaKey":"Dandiset","identifier":"DANDI:000935","repository":"https://dandiarchive.org","contributor":[{"name":"National Institutes of Health (NIH)","roleName":["dcite:Funder"],"schemaKey":"Organization","awardNumber":"1 R01 NS 120832-21"},{"name":"Prakash, Mansi","roleName":["dcite:Researcher"],"schemaKey":"Person","includeInCitation":true},{"name":"Murphy, Jeremy","roleName":["dcite:Researcher"],"schemaKey":"Person","includeInCitation":true},{"name":"Friedman, Nina","schemaKey":"Person","includeInCitation":true},{"name":"St Laurent, Robyn","schemaKey":"Person","includeInCitation":false},{"name":"Bjorefeldt, Andreas","schemaKey":"Person","includeInCitation":false},{"name":"Pal, Akash","schemaKey":"Person","includeInCitation":true},{"name":"Bhagat, Yuvraj","schemaKey":"Person","includeInCitation":true},{"name":"Kauer, Julie A.","schemaKey":"Person","includeInCitation":false},{"name":"Shaner, Nathan C.","schemaKey":"Person","includeInCitation":true},{"name":"Lipscombe, Diane","schemaKey":"Person","includeInCitation":true},{"name":"Hochgeschwender, Ute","email":"hochg1u@cmich.edu","roleName":["dcite:ContactPerson","dcite:ProjectLeader"],"schemaKey":"Person","includeInCitation":true},{"name":"Moore, Christopher I.","email":"christopher_moore@brown.edu","roleName":["dcite:ProjectLeader","dcite:ContactPerson"],"schemaKey":"Person","includeInCitation":true},{"name":"Crespo, Emmanuel L.","schemaKey":"Person","includeInCitation":true}],"dateCreated":"2024-03-06T16:20:51.867802+00:00","description":"This is the repository for in vivo extracellular electrophysiology testing a bioluminescent-optogenetic synaptic element. In this experiment (see doi: 10.1038/s42003-021-02981-7), extracellular electrophysiology data and 1-photon bioluminescent imaging data were recorded from six PV-Cre mice under isoflurane anesthesia. There are two groups (Opsin(+) and Opsin(-), see session description and doi: 10.1038/s42003-021-02981-7 for details) of 3 animals each. For all animals a baseline of ~3 minutes of data was recorded, after which the bioluminescent luciferin Coelenterazine was infused into a saline well over an open craniotomy exposing barrel cortex. Time Intervals in the data set designate the start and stop times of Coelenterazine infusion in seconds.","publishedBy":{"id":"urn:uuid:0ff8ef39-27b9-44ef-8b11-8f880dc7a391","name":"DANDI publish","endDate":"2024-03-19T20:26:03.532850+00:00","schemaKey":"PublishActivity","startDate":"2024-03-19T20:26:03.532850+00:00","wasAssociatedWith":[{"id":"urn:uuid:c070c792-6f1d-4c57-8589-eb822eda6381","name":"DANDI API","version":"0.1.0","schemaKey":"Software","identifier":"RRID:SCR_017571"}]},"studyTarget":["Test the efficacy of a bioluminescent-optogenetic synaptic construct in vivo"],"assetsSummary":{"species":[{"name":"Mus musculus - House mouse","schemaKey":"SpeciesType","identifier":"http://purl.obolibrary.org/obo/NCBITaxon_10090"}],"approach":[{"name":"microscopy approach; cell population imaging","schemaKey":"ApproachType"},{"name":"electrophysiological approach","schemaKey":"ApproachType"}],"schemaKey":"AssetsSummary","dataStandard":[{"name":"Neurodata Without Borders (NWB)","schemaKey":"StandardsType","identifier":"RRID:SCR_015242"}],"numberOfBytes":49105883680,"numberOfFiles":6,"numberOfSubjects":6,"variableMeasured":["ElectrodeGroup","ElectricalSeries","OpticalChannel","ImagingPlane"],"measurementTechnique":[{"name":"multi electrode extracellular electrophysiology recording technique","schemaKey":"MeasurementTechniqueType"},{"name":"surgical technique","schemaKey":"MeasurementTechniqueType"}]},"datePublished":"2024-03-19T20:26:03.532850+00:00","schemaVersion":"0.6.6","ethicsApproval":[{"schemaKey":"EthicsApproval","identifier":"20-09-0003","contactPoint":{"url":"https://www.brown.edu/research/conducting-research-brown/research-compliance-irb-iacuc-coi-export-control-research-data-management-and-data-use-agreements/institutional-animal-care-and-use-committee-iacuc","email":"IACUC@brown.edu","schemaKey":"ContactPoint"}}],"wasGeneratedBy":[],"relatedResource":[],"manifestLocation":["https://dandiarchive.s3.amazonaws.com/dandisets/000935/0.240319.2026/assets.yaml"]}
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