UK Biobank Pan-Ancestry Summary Statistics

Stream data with DDA:

from dagshub.streaming import DagsHubFilesystem

fs = DagsHubFilesystem(".", repo_url="https://dagshub.com/DagsHub-Datasets/broad-pan-ukb-dataset")

fs.listdir("s3://pan-ukb-us-east-1")

Description:

A multi-ancestry analysis of 7,221 phenotypes using a generalized mixed model association testing framework, spanning 16,119 genome-wide association studies. We provide standard meta-analysis across all populations and with a leave-one-population-out approach for each trait. The data are provided in tsv format (per phenotype) and Hail MatrixTable (all phenotypes and variants). Metadata is provided in phenotype and variant manifests.

Contact:

A multi-ancestry analysis of 7,221 phenotypes using a generalized mixed model association testing framework, spanning 16,119 genome-wide association studies. We provide standard meta-analysis across all populations and with a leave-one-population-out approach for each trait. The data are provided in tsv format (per phenotype) and Hail MatrixTable (all phenotypes and variants). Metadata is provided in phenotype and variant manifests.

Update Frequency:

Occasional

Managed By:

Analytic and Translational Genetics Unit, Massachusetts General Hospital and the Broad Institute

Resources:

1. resource:
   • Description: Summary statistics from Genome Wide Association Studies (GWASes) of multiple ancestries in the UK Biobank, in TSV and Hail formats
   • ARN: arn:aws:s3:::pan-ukb-us-east-1
   • Region: us-east-1
   • Type: S3 Bucket

Tags:

aws-pds, genetic, genome wide association study, genomic, life sciences, population genetics

Tutorials:

1. tutorial:
   • Title: Hail Tutorials
   • URL: https://hail.is/docs/0.2/tutorials-landing.html
   • AuthorName: Hail Team
   • AuthorURL: https://hail.is/

Tools & Applications:

1. tools & applications:

   • Title: Hail
   • URL: https://hail.is
   • AuthorName: Hail Team
   • AuthorURL: https://hail.is/

2. tools & applications:

   • Title: Hail on AWS Quick Start
   • URL: https://aws.amazon.com/quickstart/architecture/hail/
   • AuthorName: Amazon Web Services and PrivoIT

Publication:

1. publication:
   • Title: Pan-ancestry genetic analysis of the UK Biobank
   • URL: https://pan.ukbb.broadinstitute.org/
   • AuthorName: Pan UKBB Team