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<?xml version="1.0" encoding="UTF-8"?>
<bio:tcga_bcr xsi:schemaLocation="http://tcga.nci/bcr/xml/biospecimen/2.7 https://raw.githubusercontent.com/nchbcr/xsd/2.7/tcga.nci/bcr/xml/biospecimen/2.7/TCGA_BCR.Biospecimen.xsd" schemaVersion="2.7" xmlns:bio="http://tcga.nci/bcr/xml/biospecimen/2.7" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:admin="http://tcga.nci/bcr/xml/administration/2.7" xmlns:shared="http://tcga.nci/bcr/xml/shared/2.7" xmlns:bio_model="http://tcga.nci/bcr/xml/biospecimen/bio_model/2.7" xmlns:bio_shared="http://tcga.nci/bcr/xml/biospecimen/shared/2.7">
<admin:admin>
<admin:bcr xsd_ver="1.17">Nationwide Children's Hospital</admin:bcr>
<admin:file_uuid xsd_ver="2.6">47870701-9C23-4AD2-B8E1-07275E5AB1B0</admin:file_uuid>
<admin:batch_number xsd_ver="1.17">661.0.0</admin:batch_number>
<admin:project_code xsd_ver="2.7">Human Cancer Model Initiative</admin:project_code>
<admin:disease_code xsd_ver="2.6">HCMI</admin:disease_code>
<admin:day_of_dcc_upload xsd_ver="1.17">10</admin:day_of_dcc_upload>
<admin:month_of_dcc_upload xsd_ver="1.17">10</admin:month_of_dcc_upload>
<admin:year_of_dcc_upload xsd_ver="1.17">2019</admin:year_of_dcc_upload>
<admin:program xsd_ver="2.7">HCMI</admin:program>
<admin:dbgap_registration_code xsd_ver="2.7">001486</admin:dbgap_registration_code>
</admin:admin>
<bio:patient>
<admin:additional_studies/>
<shared:bcr_patient_barcode cde="2003301" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71</shared:bcr_patient_barcode>
<shared:bcr_patient_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">d420e653-3fb2-432b-9e81-81232a80264d</shared:bcr_patient_uuid>
<shared:tissue_source_site cde="" xsd_ver="2.4" procurement_status="Completed" owner="">BROD</shared:tissue_source_site>
<shared:patient_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">0210-C71</shared:patient_id>
<shared:gender cde="2200604" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:days_to_index cde="" xsd_ver="2.6" procurement_status="Not Available" owner=""/>
<bio:bcr_canonical_check>
<bio:bcr_patient_canonical_status cde="" xsd_ver="2.6" procurement_status="Completed" owner="">Canonical</bio:bcr_patient_canonical_status>
</bio:bcr_canonical_check>
<bio:samples>
<bio_model:sample>
<bio:sample_type_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">85</bio:sample_type_id>
<bio:vial_number cde="" xsd_ver="2.4" procurement_status="Completed" owner="">R</bio:vial_number>
<bio:biospecimen_sequence cde="" xsd_ver="2.6" procurement_status="Completed" owner="">1</bio:biospecimen_sequence>
<bio:sample_type cde="" xsd_ver="2.4" procurement_status="Completed" owner="">Next Generation Cancer Model</bio:sample_type>
<bio:initial_weight cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:tissue_type cde="" xsd_ver="2.6" procurement_status="Completed" owner="">Tumor</bio:tissue_type>
<bio:composition cde="" xsd_ver="2.6" procurement_status="Completed" owner="">3D Neurosphere</bio:composition>
<bio:tumor_descriptor cde="" xsd_ver="2.6" procurement_status="Completed" owner="">Recurrence</bio:tumor_descriptor>
<bio:days_to_collection cde="" xsd_ver="2.6" procurement_status="Not Available" owner=""/>
<bio:preservation_method cde="" xsd_ver="2.6" procurement_status="Completed" owner="">Frozen</bio:preservation_method>
<bio:bcr_sample_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-85R</bio:bcr_sample_barcode>
<bio:bcr_sample_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">DC5C7F67-8417-4194-844D-546EB00EA320</bio:bcr_sample_uuid>
<bio_model:ref_uuid cde="" xsd_ver="2.7" procurement_status="Completed" owner="">5156AFBB-D9C2-4135-BC7B-E8F1E7BFF119</bio_model:ref_uuid>
<bio:analytes>
<bio:analyte>
<admin:additional_studies/>
<bio:subportion_sequence cde="" xsd_ver="2.6" procurement_status="Not Available" owner=""/>
<bio:analyte_type_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">D</bio:analyte_type_id>
<bio:analyte_type cde="" xsd_ver="1.10" procurement_status="Completed" owner="">DNA</bio:analyte_type>
<bio:concentration cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0.14</bio:concentration>
<bio:a260_a280_ratio cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:gel_image_file cde="" xsd_ver="1.8" procurement_status="Completed" owner="">https://sharedoc.nchri.org/tcga-bcr/default.aspx</bio:gel_image_file>
<bio:well_number cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:bcr_analyte_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-85R-01D</bio:bcr_analyte_barcode>
<bio:bcr_analyte_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">6E715AAA-3A6F-4678-A027-8117F36257B1</bio:bcr_analyte_uuid>
<bio:is_derived_from_ffpe cde="4170571" xsd_ver="2.6" procurement_status="Completed" owner="">NO</bio:is_derived_from_ffpe>
<bio:aliquots>
<bio:aliquot>
<admin:additional_studies/>
<bio:plate_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">A78T</bio:plate_id>
<bio:center_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">36</bio:center_id>
<bio:day_of_shipment cde="" xsd_ver="1.8" procurement_status="Completed" owner="">02</bio:day_of_shipment>
<bio:month_of_shipment cde="" xsd_ver="1.8" procurement_status="Completed" owner="">10</bio:month_of_shipment>
<bio:year_of_shipment cde="" xsd_ver="1.8" procurement_status="Completed" owner="">2019</bio:year_of_shipment>
<bio:bcr_aliquot_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-85R-01D-A78T-36</bio:bcr_aliquot_barcode>
<bio:bcr_aliquot_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">37E981AA-B97B-4470-9906-7DEC4600020E</bio:bcr_aliquot_uuid>
<bio:concentration cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0.03</bio:concentration>
<bio:quantity units="ug" cde="" xsd_ver="2.6" procurement_status="Completed" owner="">2.40</bio:quantity>
<bio:volume units="ul" cde="" xsd_ver="2.6" procurement_status="Completed" owner="">80.00</bio:volume>
<bio:plate_row cde="" xsd_ver="2.3" procurement_status="Completed" owner="">C</bio:plate_row>
<bio:plate_column cde="" xsd_ver="2.3" procurement_status="Completed" owner="">4</bio:plate_column>
<bio:biospecimen_barcode_bottom cde="" xsd_ver="2.3" procurement_status="Completed" owner="">0334237705</bio:biospecimen_barcode_bottom>
<bio:source_center cde="" xsd_ver="2.4" procurement_status="Completed" owner="">23</bio:source_center>
<bio:is_derived_from_ffpe cde="4170571" xsd_ver="2.6" procurement_status="Completed" owner="">NO</bio:is_derived_from_ffpe>
</bio:aliquot>
</bio:aliquots>
<bio:protocols>
<bio:protocol>
<bio:experimental_protocol_type cde="" xsd_ver="1.8" procurement_status="Completed" owner="">aDNA Preparation Type</bio:experimental_protocol_type>
<bio:protocol_name cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:protocol_file_name cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
</bio:protocol>
</bio:protocols>
<bio:dna>
<bio:normal_tumor_genotype_match cde="" xsd_ver="1.8" procurement_status="Completed" owner="">YES</bio:normal_tumor_genotype_match>
<bio:pcr_amplification_successful cde="" xsd_ver="1.8" procurement_status="Completed" owner="">YES</bio:pcr_amplification_successful>
</bio:dna>
<bio:spectrophotometer_method cde="" xsd_ver="2.3" procurement_status="Completed" owner="">PicoGreen</bio:spectrophotometer_method>
</bio:analyte>
<bio:analyte>
<admin:additional_studies/>
<bio:subportion_sequence cde="" xsd_ver="2.6" procurement_status="Not Available" owner=""/>
<bio:analyte_type_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">R</bio:analyte_type_id>
<bio:analyte_type cde="" xsd_ver="1.10" procurement_status="Completed" owner="">RNA</bio:analyte_type>
<bio:concentration cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0.15</bio:concentration>
<bio:a260_a280_ratio cde="" xsd_ver="1.8" procurement_status="Completed" owner="">1.67</bio:a260_a280_ratio>
<bio:gel_image_file cde="" xsd_ver="1.8" procurement_status="Completed" owner="">https://sharedoc.nchri.org/tcga-bcr/default.aspx</bio:gel_image_file>
<bio:well_number cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:bcr_analyte_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-85R-01R</bio:bcr_analyte_barcode>
<bio:bcr_analyte_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">C4FA0C6D-4F90-41D5-BB66-6E4EE5574BD2</bio:bcr_analyte_uuid>
<bio:is_derived_from_ffpe cde="4170571" xsd_ver="2.6" procurement_status="Completed" owner="">NO</bio:is_derived_from_ffpe>
<bio:aliquots>
<bio:aliquot>
<admin:additional_studies/>
<bio:plate_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">A78V</bio:plate_id>
<bio:center_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">41</bio:center_id>
<bio:day_of_shipment cde="" xsd_ver="1.8" procurement_status="Completed" owner="">02</bio:day_of_shipment>
<bio:month_of_shipment cde="" xsd_ver="1.8" procurement_status="Completed" owner="">10</bio:month_of_shipment>
<bio:year_of_shipment cde="" xsd_ver="1.8" procurement_status="Completed" owner="">2019</bio:year_of_shipment>
<bio:bcr_aliquot_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-85R-01R-A78V-41</bio:bcr_aliquot_barcode>
<bio:bcr_aliquot_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">F0FB2CCC-2BD0-49B7-B22D-ED39A15794DB</bio:bcr_aliquot_uuid>
<bio:concentration cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0.15</bio:concentration>
<bio:quantity units="ug" cde="" xsd_ver="2.6" procurement_status="Completed" owner="">1.46</bio:quantity>
<bio:volume units="ul" cde="" xsd_ver="2.6" procurement_status="Completed" owner="">9.70</bio:volume>
<bio:plate_row cde="" xsd_ver="2.3" procurement_status="Completed" owner="">B</bio:plate_row>
<bio:plate_column cde="" xsd_ver="2.3" procurement_status="Completed" owner="">5</bio:plate_column>
<bio:biospecimen_barcode_bottom cde="" xsd_ver="2.3" procurement_status="Completed" owner="">0334257104</bio:biospecimen_barcode_bottom>
<bio:source_center cde="" xsd_ver="2.4" procurement_status="Completed" owner="">23</bio:source_center>
<bio:is_derived_from_ffpe cde="4170571" xsd_ver="2.6" procurement_status="Completed" owner="">NO</bio:is_derived_from_ffpe>
</bio:aliquot>
</bio:aliquots>
<bio:protocols>
<bio:protocol>
<bio:experimental_protocol_type cde="" xsd_ver="1.8" procurement_status="Completed" owner="">mirVana (Allprep DNA) RNA</bio:experimental_protocol_type>
<bio:protocol_name cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:protocol_file_name cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
</bio:protocol>
</bio:protocols>
<bio:rna>
<bio:ratio_28s_18s cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0.39</bio:ratio_28s_18s>
<bio:rinvalue cde="" xsd_ver="1.8" procurement_status="Completed" owner="">7.10</bio:rinvalue>
</bio:rna>
<bio:spectrophotometer_method cde="" xsd_ver="2.3" procurement_status="Completed" owner="">UV Spec</bio:spectrophotometer_method>
</bio:analyte>
</bio:analytes>
</bio_model:sample>
<bio:sample>
<admin:additional_studies/>
<bio:specimen_fraction_ordinal cde="" xsd_ver="2.7" procurement_status="Not Available" owner=""/>
<bio:sample_type_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">02</bio:sample_type_id>
<bio:vial_number cde="" xsd_ver="2.4" procurement_status="Completed" owner="">A</bio:vial_number>
<bio:biospecimen_sequence cde="" xsd_ver="2.6" procurement_status="Completed" owner="">1</bio:biospecimen_sequence>
<bio:sample_type cde="" xsd_ver="2.4" procurement_status="Completed" owner="">Recurrent Tumor</bio:sample_type>
<bio:longest_dimension cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:intermediate_dimension cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:shortest_dimension cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:initial_weight cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:current_weight cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:freezing_method cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:oct_embedded cde="" xsd_ver="1.8" procurement_status="Completed" owner="">false</bio:oct_embedded>
<bio:preservation_method cde="" xsd_ver="2.6" procurement_status="Completed" owner="">Frozen</bio:preservation_method>
<bio:tissue_type cde="" xsd_ver="2.6" procurement_status="Completed" owner="">Tumor</bio:tissue_type>
<bio:composition cde="" xsd_ver="2.6" procurement_status="Completed" owner="">Solid Tissue</bio:composition>
<bio:tumor_descriptor cde="" xsd_ver="2.6" procurement_status="Completed" owner="">Recurrence</bio:tumor_descriptor>
<bio:days_to_collection cde="" xsd_ver="2.6" procurement_status="Not Available" owner=""/>
<bio:time_between_clamping_and_freezing cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:time_between_excision_and_freezing cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:bcr_sample_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-02A</bio:bcr_sample_barcode>
<bio:bcr_sample_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">5156AFBB-D9C2-4135-BC7B-E8F1E7BFF119</bio:bcr_sample_uuid>
<bio:is_ffpe cde="4170557" xsd_ver="2.6" procurement_status="Completed" owner="">NO</bio:is_ffpe>
<bio:portions>
<bio:portion>
<admin:additional_studies/>
<bio:portion_number cde="" xsd_ver="2.4" procurement_status="Not Available" owner=""/>
<bio:portion_sequence cde="" xsd_ver="2.6" procurement_status="Completed" owner="">1</bio:portion_sequence>
<bio:day_of_creation cde="" xsd_ver="1.8" procurement_status="Completed" owner="">29</bio:day_of_creation>
<bio:month_of_creation cde="" xsd_ver="1.8" procurement_status="Completed" owner="">08</bio:month_of_creation>
<bio:year_of_creation cde="" xsd_ver="1.8" procurement_status="Completed" owner="">2019</bio:year_of_creation>
<bio:weight cde="" xsd_ver="1.8" procurement_status="Completed" owner="">30.00</bio:weight>
<bio:bcr_portion_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-02A-11</bio:bcr_portion_barcode>
<bio:bcr_portion_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">6959EFAF-0949-461B-B434-218FA5F175C8</bio:bcr_portion_uuid>
<bio:is_ffpe cde="4170557" xsd_ver="2.6" procurement_status="Completed" owner="">NO</bio:is_ffpe>
<bio:analytes>
<bio:analyte>
<admin:additional_studies/>
<bio:subportion_sequence cde="" xsd_ver="2.6" procurement_status="Completed" owner="">1</bio:subportion_sequence>
<bio:analyte_type_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">D</bio:analyte_type_id>
<bio:analyte_type cde="" xsd_ver="1.10" procurement_status="Completed" owner="">DNA</bio:analyte_type>
<bio:concentration cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0.15</bio:concentration>
<bio:a260_a280_ratio cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:gel_image_file cde="" xsd_ver="1.8" procurement_status="Completed" owner="">https://sharedoc.nchri.org/tcga-bcr/default.aspx</bio:gel_image_file>
<bio:well_number cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:bcr_analyte_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-02A-11D</bio:bcr_analyte_barcode>
<bio:bcr_analyte_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">810F9CC0-12DE-4110-9411-0FF2AD68F82A</bio:bcr_analyte_uuid>
<bio:is_derived_from_ffpe cde="4170571" xsd_ver="2.6" procurement_status="Completed" owner="">NO</bio:is_derived_from_ffpe>
<bio:aliquots>
<bio:aliquot>
<admin:additional_studies/>
<bio:plate_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">A78T</bio:plate_id>
<bio:center_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">36</bio:center_id>
<bio:day_of_shipment cde="" xsd_ver="1.8" procurement_status="Completed" owner="">02</bio:day_of_shipment>
<bio:month_of_shipment cde="" xsd_ver="1.8" procurement_status="Completed" owner="">10</bio:month_of_shipment>
<bio:year_of_shipment cde="" xsd_ver="1.8" procurement_status="Completed" owner="">2019</bio:year_of_shipment>
<bio:bcr_aliquot_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-02A-11D-A78T-36</bio:bcr_aliquot_barcode>
<bio:bcr_aliquot_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">738B49E9-7670-40DB-8A45-87DB49CB4748</bio:bcr_aliquot_uuid>
<bio:concentration cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0.03</bio:concentration>
<bio:quantity units="ug" cde="" xsd_ver="2.6" procurement_status="Completed" owner="">2.40</bio:quantity>
<bio:volume units="ul" cde="" xsd_ver="2.6" procurement_status="Completed" owner="">80.00</bio:volume>
<bio:plate_row cde="" xsd_ver="2.3" procurement_status="Completed" owner="">C</bio:plate_row>
<bio:plate_column cde="" xsd_ver="2.3" procurement_status="Completed" owner="">2</bio:plate_column>
<bio:biospecimen_barcode_bottom cde="" xsd_ver="2.3" procurement_status="Completed" owner="">0334237689</bio:biospecimen_barcode_bottom>
<bio:source_center cde="" xsd_ver="2.4" procurement_status="Completed" owner="">23</bio:source_center>
<bio:is_derived_from_ffpe cde="4170571" xsd_ver="2.6" procurement_status="Completed" owner="">NO</bio:is_derived_from_ffpe>
</bio:aliquot>
</bio:aliquots>
<bio:protocols>
<bio:protocol>
<bio:experimental_protocol_type cde="" xsd_ver="1.8" procurement_status="Completed" owner="">aDNA Preparation Type</bio:experimental_protocol_type>
<bio:protocol_name cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:protocol_file_name cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
</bio:protocol>
</bio:protocols>
<bio:dna>
<bio:normal_tumor_genotype_match cde="" xsd_ver="1.8" procurement_status="Completed" owner="">YES</bio:normal_tumor_genotype_match>
<bio:pcr_amplification_successful cde="" xsd_ver="1.8" procurement_status="Completed" owner="">YES</bio:pcr_amplification_successful>
</bio:dna>
<bio:spectrophotometer_method cde="" xsd_ver="2.3" procurement_status="Completed" owner="">PicoGreen</bio:spectrophotometer_method>
</bio:analyte>
<bio:analyte>
<admin:additional_studies/>
<bio:subportion_sequence cde="" xsd_ver="2.6" procurement_status="Completed" owner="">1</bio:subportion_sequence>
<bio:analyte_type_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">R</bio:analyte_type_id>
<bio:analyte_type cde="" xsd_ver="1.10" procurement_status="Completed" owner="">RNA</bio:analyte_type>
<bio:concentration cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0.17</bio:concentration>
<bio:a260_a280_ratio cde="" xsd_ver="1.8" procurement_status="Completed" owner="">1.83</bio:a260_a280_ratio>
<bio:gel_image_file cde="" xsd_ver="1.8" procurement_status="Completed" owner="">https://sharedoc.nchri.org/tcga-bcr/default.aspx</bio:gel_image_file>
<bio:well_number cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:bcr_analyte_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-02A-11R</bio:bcr_analyte_barcode>
<bio:bcr_analyte_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">C3B663EB-E135-4897-8D20-D413155CEBD9</bio:bcr_analyte_uuid>
<bio:is_derived_from_ffpe cde="4170571" xsd_ver="2.6" procurement_status="Completed" owner="">NO</bio:is_derived_from_ffpe>
<bio:aliquots>
<bio:aliquot>
<admin:additional_studies/>
<bio:plate_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">A78V</bio:plate_id>
<bio:center_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">41</bio:center_id>
<bio:day_of_shipment cde="" xsd_ver="1.8" procurement_status="Completed" owner="">02</bio:day_of_shipment>
<bio:month_of_shipment cde="" xsd_ver="1.8" procurement_status="Completed" owner="">10</bio:month_of_shipment>
<bio:year_of_shipment cde="" xsd_ver="1.8" procurement_status="Completed" owner="">2019</bio:year_of_shipment>
<bio:bcr_aliquot_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-02A-11R-A78V-41</bio:bcr_aliquot_barcode>
<bio:bcr_aliquot_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">C273A21F-E1F5-43B1-A8AF-4D6D29F92A6D</bio:bcr_aliquot_uuid>
<bio:concentration cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0.17</bio:concentration>
<bio:quantity units="ug" cde="" xsd_ver="2.6" procurement_status="Completed" owner="">1.50</bio:quantity>
<bio:volume units="ul" cde="" xsd_ver="2.6" procurement_status="Completed" owner="">8.80</bio:volume>
<bio:plate_row cde="" xsd_ver="2.3" procurement_status="Completed" owner="">B</bio:plate_row>
<bio:plate_column cde="" xsd_ver="2.3" procurement_status="Completed" owner="">4</bio:plate_column>
<bio:biospecimen_barcode_bottom cde="" xsd_ver="2.3" procurement_status="Completed" owner="">0334257096</bio:biospecimen_barcode_bottom>
<bio:source_center cde="" xsd_ver="2.4" procurement_status="Completed" owner="">23</bio:source_center>
<bio:is_derived_from_ffpe cde="4170571" xsd_ver="2.6" procurement_status="Completed" owner="">NO</bio:is_derived_from_ffpe>
</bio:aliquot>
</bio:aliquots>
<bio:protocols>
<bio:protocol>
<bio:experimental_protocol_type cde="" xsd_ver="1.8" procurement_status="Completed" owner="">mirVana (Allprep DNA) RNA</bio:experimental_protocol_type>
<bio:protocol_name cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:protocol_file_name cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
</bio:protocol>
</bio:protocols>
<bio:rna>
<bio:ratio_28s_18s cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0.91</bio:ratio_28s_18s>
<bio:rinvalue cde="" xsd_ver="1.8" procurement_status="Completed" owner="">6.90</bio:rinvalue>
</bio:rna>
<bio:spectrophotometer_method cde="" xsd_ver="2.3" procurement_status="Completed" owner="">UV Spec</bio:spectrophotometer_method>
</bio:analyte>
</bio:analytes>
<bio:slides>
<bio:slide>
<admin:additional_studies/>
<bio:section_location cde="" xsd_ver="1.8" procurement_status="Completed" owner="">TOP</bio:section_location>
<bio:number_proliferating_cells cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:percent_tumor_cells cde="" xsd_ver="1.8" procurement_status="Completed" owner="">20</bio:percent_tumor_cells>
<bio:percent_tumor_nuclei cde="2841225" xsd_ver="1.8" procurement_status="Completed" owner="">47</bio:percent_tumor_nuclei>
<bio:percent_normal_cells cde="" xsd_ver="1.8" procurement_status="Completed" owner="">22</bio:percent_normal_cells>
<bio:percent_necrosis cde="2841237" xsd_ver="1.8" procurement_status="Completed" owner="">2</bio:percent_necrosis>
<bio:percent_stromal_cells cde="" xsd_ver="1.8" procurement_status="Completed" owner="">56</bio:percent_stromal_cells>
<bio:percent_inflam_infiltration cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:percent_lymphocyte_infiltration cde="" xsd_ver="1.8" procurement_status="Completed" owner="">1</bio:percent_lymphocyte_infiltration>
<bio:percent_monocyte_infiltration cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0</bio:percent_monocyte_infiltration>
<bio:percent_granulocyte_infiltration cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:percent_neutrophil_infiltration cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0</bio:percent_neutrophil_infiltration>
<bio:percent_eosinophil_infiltration cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<shared:bcr_slide_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-02A-01-S1-HE</shared:bcr_slide_barcode>
<shared:bcr_slide_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">6FCD675A-9E02-4B8F-A222-47DE93B518A3</shared:bcr_slide_uuid>
<shared:image_file_name cde="" xsd_ver="2.6" procurement_status="Completed" owner="">HCM-BROD-0210-C71-02A-01-S1-HE.6FCD675A-9E02-4B8F-A222-47DE93B518A3.svs</shared:image_file_name>
<bio:is_derived_from_ffpe cde="4170571" xsd_ver="2.6" procurement_status="Completed" owner="">NO</bio:is_derived_from_ffpe>
</bio:slide>
<bio:slide>
<admin:additional_studies/>
<bio:section_location cde="" xsd_ver="1.8" procurement_status="Completed" owner="">BOTTOM</bio:section_location>
<bio:number_proliferating_cells cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:percent_tumor_cells cde="" xsd_ver="1.8" procurement_status="Completed" owner="">47</bio:percent_tumor_cells>
<bio:percent_tumor_nuclei cde="2841225" xsd_ver="1.8" procurement_status="Completed" owner="">76</bio:percent_tumor_nuclei>
<bio:percent_normal_cells cde="" xsd_ver="1.8" procurement_status="Completed" owner="">15</bio:percent_normal_cells>
<bio:percent_necrosis cde="2841237" xsd_ver="1.8" procurement_status="Completed" owner="">1</bio:percent_necrosis>
<bio:percent_stromal_cells cde="" xsd_ver="1.8" procurement_status="Completed" owner="">37</bio:percent_stromal_cells>
<bio:percent_inflam_infiltration cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:percent_lymphocyte_infiltration cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0</bio:percent_lymphocyte_infiltration>
<bio:percent_monocyte_infiltration cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0</bio:percent_monocyte_infiltration>
<bio:percent_granulocyte_infiltration cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:percent_neutrophil_infiltration cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0</bio:percent_neutrophil_infiltration>
<bio:percent_eosinophil_infiltration cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<shared:bcr_slide_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-02A-01-S2-HE</shared:bcr_slide_barcode>
<shared:bcr_slide_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">8C4451BA-4365-4070-B318-61A1237FCBEC</shared:bcr_slide_uuid>
<shared:image_file_name cde="" xsd_ver="2.6" procurement_status="Completed" owner="">HCM-BROD-0210-C71-02A-01-S2-HE.8C4451BA-4365-4070-B318-61A1237FCBEC.svs</shared:image_file_name>
<bio:is_derived_from_ffpe cde="4170571" xsd_ver="2.6" procurement_status="Completed" owner="">NO</bio:is_derived_from_ffpe>
</bio:slide>
</bio:slides>
<bio:LCE cde="3251491" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
</bio:portion>
</bio:portions>
<bio:tumor_pathology/>
<bio:method_of_sample_procurement cde="3103514" xsd_ver="2.3" procurement_status="Not Available" owner=""/>
<bio_shared:other_method_of_sample_procurement cde="2006730" xsd_ver="2.5" procurement_status="Not Available" owner=""/>
<shared:days_to_sample_procurement cde="3288495" xsd_ver="2.6" procurement_status="Not Available" owner=""/>
<bio:pathology_report_uuid cde="" xsd_ver="2.4" procurement_status="Not Available" owner=""/>
<bio:pathology_report_file_name cde="" xsd_ver="2.6" procurement_status="Not Available" owner=""/>
<bio:diagnostic_slides>
<admin:additional_studies/>
</bio:diagnostic_slides>
</bio:sample>
<bio:sample>
<admin:additional_studies/>
<bio:specimen_fraction_ordinal cde="" xsd_ver="2.7" procurement_status="Not Available" owner=""/>
<bio:sample_type_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">10</bio:sample_type_id>
<bio:vial_number cde="" xsd_ver="2.4" procurement_status="Completed" owner="">A</bio:vial_number>
<bio:biospecimen_sequence cde="" xsd_ver="2.6" procurement_status="Completed" owner="">1</bio:biospecimen_sequence>
<bio:sample_type cde="" xsd_ver="2.4" procurement_status="Completed" owner="">Blood Derived Normal</bio:sample_type>
<bio:longest_dimension cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:intermediate_dimension cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:shortest_dimension cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:initial_weight cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:current_weight cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:freezing_method cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:oct_embedded cde="" xsd_ver="1.8" procurement_status="Completed" owner="">false</bio:oct_embedded>
<bio:preservation_method cde="" xsd_ver="2.6" procurement_status="Completed" owner="">Frozen</bio:preservation_method>
<bio:tissue_type cde="" xsd_ver="2.6" procurement_status="Completed" owner="">Normal</bio:tissue_type>
<bio:composition cde="" xsd_ver="2.6" procurement_status="Completed" owner="">Peripheral Blood Components NOS</bio:composition>
<bio:tumor_descriptor cde="" xsd_ver="2.6" procurement_status="Completed" owner="">Not Applicable</bio:tumor_descriptor>
<bio:days_to_collection cde="" xsd_ver="2.6" procurement_status="Not Available" owner=""/>
<bio:time_between_clamping_and_freezing cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:time_between_excision_and_freezing cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:bcr_sample_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-10A</bio:bcr_sample_barcode>
<bio:bcr_sample_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">72AC77F9-DD1B-4AC4-AC3E-0D197415463A</bio:bcr_sample_uuid>
<bio:is_ffpe cde="4170557" xsd_ver="2.6" procurement_status="Completed" owner="">NO</bio:is_ffpe>
<bio:portions>
<bio:portion>
<admin:additional_studies/>
<bio:portion_number cde="" xsd_ver="2.4" procurement_status="Not Available" owner=""/>
<bio:portion_sequence cde="" xsd_ver="2.6" procurement_status="Completed" owner="">1</bio:portion_sequence>
<bio:day_of_creation cde="" xsd_ver="1.8" procurement_status="Completed" owner="">14</bio:day_of_creation>
<bio:month_of_creation cde="" xsd_ver="1.8" procurement_status="Completed" owner="">08</bio:month_of_creation>
<bio:year_of_creation cde="" xsd_ver="1.8" procurement_status="Completed" owner="">2019</bio:year_of_creation>
<bio:weight cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:bcr_portion_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-10A-01</bio:bcr_portion_barcode>
<bio:bcr_portion_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">DCDAB8B0-7099-4E9C-B453-2C78C2DF4498</bio:bcr_portion_uuid>
<bio:is_ffpe cde="4170557" xsd_ver="2.6" procurement_status="Completed" owner="">NO</bio:is_ffpe>
<bio:analytes>
<bio:analyte>
<admin:additional_studies/>
<bio:subportion_sequence cde="" xsd_ver="2.6" procurement_status="Not Available" owner=""/>
<bio:analyte_type_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">D</bio:analyte_type_id>
<bio:analyte_type cde="" xsd_ver="1.10" procurement_status="Completed" owner="">DNA</bio:analyte_type>
<bio:concentration cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0.12</bio:concentration>
<bio:a260_a280_ratio cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:gel_image_file cde="" xsd_ver="1.8" procurement_status="Completed" owner="">https://sharedoc.nchri.org/tcga-bcr/default.aspx</bio:gel_image_file>
<bio:well_number cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:bcr_analyte_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-10A-01D</bio:bcr_analyte_barcode>
<bio:bcr_analyte_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">09994928-D52A-4144-823C-2542F69CC5ED</bio:bcr_analyte_uuid>
<bio:is_derived_from_ffpe cde="4170571" xsd_ver="2.6" procurement_status="Completed" owner="">NO</bio:is_derived_from_ffpe>
<bio:aliquots>
<bio:aliquot>
<admin:additional_studies/>
<bio:plate_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">A78T</bio:plate_id>
<bio:center_id cde="" xsd_ver="2.4" procurement_status="Completed" owner="">36</bio:center_id>
<bio:day_of_shipment cde="" xsd_ver="1.8" procurement_status="Completed" owner="">02</bio:day_of_shipment>
<bio:month_of_shipment cde="" xsd_ver="1.8" procurement_status="Completed" owner="">10</bio:month_of_shipment>
<bio:year_of_shipment cde="" xsd_ver="1.8" procurement_status="Completed" owner="">2019</bio:year_of_shipment>
<bio:bcr_aliquot_barcode cde="" xsd_ver="1.8" procurement_status="Completed" owner="">HCM-BROD-0210-C71-10A-01D-A78T-36</bio:bcr_aliquot_barcode>
<bio:bcr_aliquot_uuid cde="" xsd_ver="2.3" procurement_status="Completed" owner="">C24BA203-53BA-4FE1-97C4-152B45D44C39</bio:bcr_aliquot_uuid>
<bio:concentration cde="" xsd_ver="1.8" procurement_status="Completed" owner="">0.03</bio:concentration>
<bio:quantity units="ug" cde="" xsd_ver="2.6" procurement_status="Completed" owner="">1.80</bio:quantity>
<bio:volume units="ul" cde="" xsd_ver="2.6" procurement_status="Completed" owner="">60.00</bio:volume>
<bio:plate_row cde="" xsd_ver="2.3" procurement_status="Completed" owner="">C</bio:plate_row>
<bio:plate_column cde="" xsd_ver="2.3" procurement_status="Completed" owner="">3</bio:plate_column>
<bio:biospecimen_barcode_bottom cde="" xsd_ver="2.3" procurement_status="Completed" owner="">0334237697</bio:biospecimen_barcode_bottom>
<bio:source_center cde="" xsd_ver="2.4" procurement_status="Completed" owner="">23</bio:source_center>
<bio:is_derived_from_ffpe cde="4170571" xsd_ver="2.6" procurement_status="Completed" owner="">NO</bio:is_derived_from_ffpe>
</bio:aliquot>
</bio:aliquots>
<bio:protocols>
<bio:protocol>
<bio:experimental_protocol_type cde="" xsd_ver="1.8" procurement_status="Completed" owner="">Pre-extracted DNA received by TSS</bio:experimental_protocol_type>
<bio:protocol_name cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
<bio:protocol_file_name cde="" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
</bio:protocol>
</bio:protocols>
<bio:dna>
<bio:normal_tumor_genotype_match cde="" xsd_ver="1.8" procurement_status="Completed" owner="">YES</bio:normal_tumor_genotype_match>
<bio:pcr_amplification_successful cde="" xsd_ver="1.8" procurement_status="Completed" owner="">YES</bio:pcr_amplification_successful>
</bio:dna>
<bio:spectrophotometer_method cde="" xsd_ver="2.3" procurement_status="Completed" owner="">PicoGreen</bio:spectrophotometer_method>
</bio:analyte>
</bio:analytes>
<bio:slides/>
<bio:LCE cde="3251491" xsd_ver="1.8" procurement_status="Not Available" owner=""/>
</bio:portion>
</bio:portions>
<bio:tumor_pathology/>
<bio:method_of_sample_procurement cde="3103514" xsd_ver="2.3" procurement_status="Not Available" owner=""/>
<bio_shared:other_method_of_sample_procurement cde="2006730" xsd_ver="2.5" procurement_status="Not Available" owner=""/>
<shared:days_to_sample_procurement cde="3288495" xsd_ver="2.6" procurement_status="Not Available" owner=""/>
<bio:pathology_report_uuid cde="" xsd_ver="2.4" procurement_status="Not Available" owner=""/>
<bio:pathology_report_file_name cde="" xsd_ver="2.6" procurement_status="Not Available" owner=""/>
<bio:diagnostic_slides>
<admin:additional_studies/>
</bio:diagnostic_slides>
</bio:sample>
</bio:samples>
</bio:patient>
</bio:tcga_bcr>
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