Foundation Medicine Adult Cancer Clinical Dataset (FM-AD)

Stream data with DDA:

from dagshub.streaming import DagsHubFilesystem

fs = DagsHubFilesystem(".", repo_url="https://dagshub.com/DagsHub-Datasets/fm-ad-dataset")

fs.listdir("s3://gdc-fm-ad-phs001179-2-open")

Description:

The Foundation Medicine Adult Cancer Clinical Dataset (FM-AD) is a study conducted by Foundation Medicine Inc (FMI). Genomic profiling data for approximately 18,000 adult patients with a diverse array of cancers was generated using FoundationeOne, FMI's commercially available, comprehensive genomic profiling assay. This dataset contains open Clinical and Biospecimen data.

Contact:

The Foundation Medicine Adult Cancer Clinical Dataset (FM-AD) is a study conducted by Foundation Medicine Inc (FMI). Genomic profiling data for approximately 18,000 adult patients with a diverse array of cancers was generated using FoundationeOne, FMI's commercially available, comprehensive genomic profiling assay. This dataset contains open Clinical and Biospecimen data.

Update Frequency:

Genomic Data Commons (GDC) is the source of truth for this dataset; GDC offers monthly data releases, although this dataset may not be updated at every release.

Managed By:

https://ctds.uchicago.edu/

Resources:

1. resource:
   • Description: Biospecimen Supplement, Clinical Supplement
   • ARN: arn:aws:s3:::gdc-fm-ad-phs001179-2-open
   • Region: us-east-1
   • Type: S3 Bucket

Tags:

aws-pds, cancer, genomic

Tools & Applications:

1. tools & applications:
   • Title: Genomic Data Commons
   • URL: https://portal.gdc.cancer.gov/projects/FM-AD
   • AuthorName: National Cancer Institute
   • AuthorURL: https://gdc.cancer.gov/

Publication:

1. publication:

   • Title: High-Throughput Genomic Profiling of Adult Solid Tumors Reveals Novel Insights into Cancer Pathogenesis

   • URL: https://www.ncbi.nlm.nih.gov/pubmed?cmd=DetailsSearch&term=28235761[PMID]

   • AuthorName: Ryan J. Hartmaier, Lee A. Albacker, Juliann Chmielecki, Mark Bailey, Jie He, Michael E. Goldberg, Shakti Ramkissoon, James Suh, Julia A. Elvin, Samuel Chiacchia, Garrett M. Frampton, Jeffrey S. Ross, Vincent Miller, Philip J. Stephens and Doron Lipson

2. publication:

   • Title: Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity.

   • URL: https://www.ncbi.nlm.nih.gov/pubmed?cmd=DetailsSearch&term=22981675[PMID]

   • AuthorName: Beltran H, Yelensky R, Frampton GM, Park K, Downing SR, MacDonald TY, Jarosz M, Lipson D, Tagawa ST, Nanus DM, Stephens PJ, Mosquera JM, Cronin MT, Rubin MA