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Tabula Muris Senis Dataset for Machine Learning

Install DagsHub:

pip install dagshub
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To stream this data directly on DagsHub

from dagshub.streaming import DagsHubFilesystem

fs = DagsHubFilesystem(".", repo_url="https://dagshub.com/DagsHub-Datasets/tabula-muris-senis-dataset")

fs.listdir("s3://czb-tabula-muris-senis")
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Description

Tabula Muris Senis is a comprehensive compendium of single cell transcriptomic data from the model organism *Mus musculus* comprising more than 500,000 cells from 18 organs and tissues across the mouse lifespan. We discovered cell-specific changes occurring across multiple cell types and organs, as well as age related changes in the cellular composition of different organs. Using single-cell transcriptomic data we were able to assess cell type specific manifestations of different hallmarks of aging, such as senescence, changes in the activity of metabolic pathways, depletion of stem-cell populations, genomic instability and the role of inflammation as well as other changes in the organism’s immune system. Tabula Muris Senis provides a wealth of new molecular information about how the most significant hallmarks of aging are reflected in a broad range of tissues and cell types.See: https://www.biorxiv.org/content/10.1101/661728v1

Additional information

Update frequency

This is the first version of the dataset and it will be updated after the manuscript has been peer reviewed.

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